परिभाषा

Subacute sclerosing panencephalitis (SSPE) is a condition that affects the brain and spine. It is a gradual break down of nerve cells from constant swelling.

When left untreated, SSPE almost always leads to death. Contact your doctor right away if you think you or your child may have this condition.

सबएक्यूट स्केलेरोज़िंग पैनेंसेफलाइटिस

का कारण बनता है

SSPE is caused either by an altered form of the measles virus or an abnormal immune response to measles. It occurs anywhere from 2-10 years after contracting measles.

जोखिम कारक

Factors that may increase the risk of SSPE include:

  • Age: 5-15 years old
  • लिंग पुरुष
  • Measles infection in infancy
  • Not being vaccinated against measles
  • Ethnicity:
    • Arabs and Sephardic Jews have an incidence that is six times higher than Ashkenazi Jews.
    • Caucasians have a four-fold higher incidence than African Americans in the United States.

लक्षण

Symptoms of SSPE may include:

  • Abnormal behavior
  • चिड़चिड़ापन
  • Loss of intellectual abilities
  • स्मरण शक्ति की क्षति
  • Involuntary movements
  • बरामदगी
  • Inability to walk
  • Speech impairment with poor understanding
  • निगलने में कठिनाई
  • अंधापन
  • Muteness
  • Loss of consciousness

निदान

Your doctor will ask about your child’s symptoms and medical history. A physical exam will be done.

Your bodily fluids may be tested. This can be done with blood tests.

आपकी शारीरिक संरचनाओं की छवियाँ लेने की आवश्यकता हो सकती है। इसके साथ ऐसा किया जा सकता है:

  • इलेक्ट्रोकार्डियोग्राम (ईसीजी, ईकेजी)
  • परिकलित टोमोग्राफी (सीटी स्कैन
  • चुंबकीय अनुनाद इमेजिंग (एमआरआई) स्कैन

उपचार

Talk with your doctor about the best treatment plan. Treatment options include:

Supportive Therapy

With advanced disease, tube feedings and nursing care may be necessary.

दवाएं

Anticonvulsant medications can reduce some symptoms of SSPE. In addition, there is some evidence that certain medications may help stabilize the disease and/or delay its progression. These may include:

  • Inosine pranobex
  • Interferon alpha
  • Interferon beta
  • Ribavirin

रोकथाम

The best way to prevent SSPE is to get immunized to avoid contracting measles. The measles vaccine is generally given at 12-15 months of age and again at 4-6 or 11-12 years. If you have not been vaccinated, avoid contact with people who are infected with measles until all of their symptoms are gone.

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