परिभाषा
Rhabdomyolysis occurs when skeletal muscles are damaged and release myoglobin into the bloodstream. Myoglobin is an iron-containing pigment that can cause severe damage to the kidneys.
का कारण बनता है
Rhabdomyolysis results from any condition that causes significant muscle damage. These include:
- Certain muscle diseases
- Severe muscle injuries (such as a crush injury)
- Overuse of alcohol or illicit drugs
- Use of some prescription drugs
- Severe seizures or convulsions
- Extensive surgical procedures using large, muscle-dividing incisions (rare)
जोखिम कारक
A risk factor is something that increases your chance of getting a disease or condition. Factors that may increase the risk of muscle damage include:
- Extreme exertion (such as running a marathon)
- Heat stroke
- Alcohol or drug abuse
- Uncontrolled seizure disorder
लक्षण
The most common symptoms include:
- Dark urine (brown or red in color)
- Muscle pain
- मांसपेशियों में कमजोरी
Other symptoms include:
- Muscle swelling
- पीठ दर्द
- Nausea
- उल्टी करना
In severe cases, rhabdomyolysis may result in:
- Kidney damage or failure due to blocked arterial blood flow
- Multi-organ failure
- Abnormal heartbeat (arrhythmia)
निदान
डॉक्टर आपके लक्षणों और चिकित्सा इतिहास के बारे में पूछेंगे। एक शारीरिक परीक्षा ली जाएगी। परीक्षण में शामिल हो सकते हैं:
- मूत्र परीक्षण
- रक्त परीक्षण
- Muscle testing (electromyography)
उपचार
उपचार में शामिल हो सकते हैं:
Hydration
Giving large amounts of fluid is the main treatment. Fluids are usually given by IV. Hydration helps to quickly flush myoglobin out of the गुर्दे to restore their function.
दवा
Medication may include:
- Diuretics—to help flush out the kidneys
- Bicarbonate—to minimize myoglobin’s toxic effects
डायलिसिस
Dialysis is a procedure that uses an artificial kidney machine to filter blood. The clean blood is then returned to your body.
रोकथाम
Steps for prevention include:
- Drink plenty of fluids when:
- व्यायाम
- Sitting or working in hot, humid weather
- Avoid overuse of alcohol
- Avoid illicit drugs