تعريف

Immunoglobulins are special proteins in the blood that fight infections. Some of our white blood cells make them. They are also known as antibodies. Antibodies are important for the الجهاز المناعي. In immunoglobulin therapy (IVIg), extra immunoglobulins from a donor are injected into your blood.

Immune System

أسباب هذا الإجراء

It is used to treat disorders of the immune system, such as:

  • Autoimmune disease—the body begins to attack its own cells
  • Immunodeficiency—low-functioning immune system
  • Inflammatory diseases
  • Other diseases that weaken the immune system

IVIg can also reduce inflammation in the body. Some conditions, including acute infections, may need IVIg to restore antibodies and boost the immune system.

المضاعفات المحتملة

Complications are rare, but no procedure is completely free of risk. If you are planning to have IVIg, your سيقوم الطبيب بمراجعة القائمة من المضاعفات المحتملة، والتي قد تشمل:

  • الصداع
  • العدوى
  • Fluid in the lungs
  • Damage to the kidneys
  • Blood clots
  • Allergic reaction to the IVIg

ما يمكن توقعه

قبل الإجراء

No special instructions are given prior to the procedure. Before the solution is given, it is closely screened for any viruses, diseases, or infections.

وصف الإجراء

Concentrated immunoglobulin antibodies will be collected from a healthy individual. These antibodies are added to a sterile solution.

An IV needle will be inserted into a vein in your arm. The combined solution will be delivered from a hanging bag through the IV to your vein.

كم من الوقت سيستغرق ؟

About 5-6 hours

هل ستسبب الالم؟

The procedure is not painful. There may be some minor discomfort as the IV is inserted into the skin.

رعاية ما بعد العملية

The site where the IV was put in may become irritated. You should check with your doctor if this happens.

You may begin to see an improvement in your original symptoms as soon as 24-48 hours following the procedure. For some, it may be 3-4 weeks before an improvement is seen.

Immunoglobulin therapy is usually done in cycles. For an infection or other immune system deficiency, therapy is usually recommended every 3-4 weeks. If you have a neurological or autoimmune disease, therapy is administered for five days a month for 3-6 months. Following the initial therapy, maintenance therapy is administered every 3-4 weeks.

استدعاء الطبيب

As with the introduction of any foreign substance or chemical to the body, the possibility of allergic reaction exists. If you experience any of the following symptoms of anaphylactic shock (severe allergic reaction), you should call the doctor immediately:

  • Wheezing and/or difficulty breathing
  • ارتباك
  • Slurred or abnormal speech
  • Rapid heartbeat or heart palpitations, weak or rapid pulse
  • Blue tint to the skin, lips, or fingernails
  • Dizziness, lightheadedness, or feeling faint
  • Hives, rash, or itching
  • قلق
  • Nausea, vomiting, diarrhea, or abdominal cramping
  • Cough or nasal congestion
  • Reddened skin

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